Gene Drives (Rebroadcast) #510
January 25, 2019
This week on Science for the People: who is driving this genetic bus? We'll talk with Kevin Esvelt about gene drives, what they are, where they come from what they can be used for, and why the science on gene drives should be done as openly as possible. Then, we'll speak with Laurie Zoloth about the ethical questions surrounding their use, why people are so afraid, and who should be making the decision to use this technology in the wild.
- How gene drives work
- Gene Drives FAQ
- How scientists are using gene drives safely
- Current issues in gene drive technology
- Mosquitoes with gene drives to fight malaria
- An open letter on using gene drives to eradicate malaria
- Why malaria mosquitoes deserve to die
- Using gene drives to eradicate lyme disease
- Gene drive resistance
- Kevin Esvelt
- Laurie Zoloth
Kevin received his PhD in biochemistry from Harvard University in 2010 for his invention of Phage-Assisted Continuous Evolution (PACE), a synthetic microbial ecosystem for rapidly evolving biomolecules, in the laboratory of David R. Liu. At the MIT Media Lab, the Sculpting Evolution group explores evolutionary and ecological engineering and responsive science. Kevin's group investigates the fundamental parameters governing molecular evolution, uncovers new ways of controlling bacterial fitness and horizontal gene transfer, develops safeguards and model systems for evaluating CRISPR gene drive elements, collaborates with groups developing gene drive interventions, and advocates for a new model of responsive science. Broadly speaking, the group seeks to learn enough to rectify a fundamental flaw in our universe: evolution has no moral compass.
Laurie Zoloth is the incoming Dean of the University of Chicago Divinity School and currently serves as a Charles McCormick Deering Professor of Teaching Excellence at Northwestern University, holding appointments in the Department of Religious Studies in the Weinberg College of Arts and Sciences and in the Feinberg School of Medicine. Her research explores religion and ethics, drawing from sources ranging rom Biblical and Talmudic texts to postmodern Jewish philosophy, including the writings of Emmanuel Levinas. Her scholarship spans the ethics of genetic engineering, stem cell research, synthetic biology, social justice in health care, and how science and medicine are taught. As a founding board member of the Society for Scriptural Reasoning, she also researches the practices of interreligious dialogue, exploring how religion plays a role in public discussion and policy. She is the author of "Health Care and the Ethics of Encounter: A Jewish Discussion of Social Justice" and co-editor of five books, including "Notes from a Narrow Ridge: Religion and Bioethics" and "Jews and Genes: The Genetic Future in Contemporary Jewish Thought".
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